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What is the #1 vitamin a celiac should be taking to supplement his/her diet?
I found this article and thought it might be of interest to all.
Do Vitamin Supplements Benefit Celiac Patients?
Celiac.com 03/10/2009 - A recent study confirms that B-vitamin supplements are helpful in raising vitamin B6, B12 and folate levels and in reducing homocysteine levels in people with celiac disease.
Celiac disease is a typical malabsorption syndrome, and is associated with higher rates of numerous deficiencies, including folate and vitamin B12. People with celiac disease face higher rates of Hyperhomocysteinemia than do healthy controls.
A team of Dutch researchers led by Dr. Muhammed Hadithi recently set out to evaluate the efficacy of daily supplements of vitamin B6, B12 and folate on homocysteine levels in patients with celiac disease.
The study measured levels of vitamin B6, folate, vitamin B12, and fasting plasma homocysteine in 51 adults with celiac disease and 50 healthy control subjects of similar age and sex.
The results show that the celiac disease subjects who used vitamin supplements had higher blood levels of vitamin B6 (P = 0.003), folate (P < 0.001), and vitamin B12 (P = 0.012) than celiac patients who did not use supplements, or healthy controls (P = 0.035, P < 0.001, P = 0.007, for vitamin B6, folate, and vitamin B12, respectively).
Patients who use vitamin supplements also showed lower levels of plasma homocysteine than in patients who did not (P = 0.001) or healthy controls (P = 0.003). Vitamin B6 and folate were both associated with homocysteine levels, whereas vitamin B12 was not. Twenty-four (48%) of 50 controls and 23 (50%) of 46 of the celiac disease patients carried the MTHFR thermolabile variant T-allele (P = 0.89).
The research team concludes that Homocysteine levels are dependent on Marsh classification and the regular use of B-vitamin supplements reduces of homocysteine levels in patients with celiac disease.The study confirms earlier studies suggesting that both the presence and severity of celiac disease determined homocysteine levels.
The regular use of supplemental B vitamins resulted in higher levels of serum vitamin B6, folate, vitamin B12 and lower levels of plasma homocysteine in patients with celiac disease. Moreover, supplemental B vitamins seem to offer protection against the effects of villous atrophy on homocysteine levels, independent of the genetic susceptibility status as determined by carriage of the C677T polymorphism of 5,10 methylenetetrahydrofolate reductase.
What do YOU think?
Bev
Do Vitamin Supplements Benefit Celiac Patients?
Celiac.com 03/10/2009 - A recent study confirms that B-vitamin supplements are helpful in raising vitamin B6, B12 and folate levels and in reducing homocysteine levels in people with celiac disease.
Celiac disease is a typical malabsorption syndrome, and is associated with higher rates of numerous deficiencies, including folate and vitamin B12. People with celiac disease face higher rates of Hyperhomocysteinemia than do healthy controls.
A team of Dutch researchers led by Dr. Muhammed Hadithi recently set out to evaluate the efficacy of daily supplements of vitamin B6, B12 and folate on homocysteine levels in patients with celiac disease.
The study measured levels of vitamin B6, folate, vitamin B12, and fasting plasma homocysteine in 51 adults with celiac disease and 50 healthy control subjects of similar age and sex.
The results show that the celiac disease subjects who used vitamin supplements had higher blood levels of vitamin B6 (P = 0.003), folate (P < 0.001), and vitamin B12 (P = 0.012) than celiac patients who did not use supplements, or healthy controls (P = 0.035, P < 0.001, P = 0.007, for vitamin B6, folate, and vitamin B12, respectively).
Patients who use vitamin supplements also showed lower levels of plasma homocysteine than in patients who did not (P = 0.001) or healthy controls (P = 0.003). Vitamin B6 and folate were both associated with homocysteine levels, whereas vitamin B12 was not. Twenty-four (48%) of 50 controls and 23 (50%) of 46 of the celiac disease patients carried the MTHFR thermolabile variant T-allele (P = 0.89).
The research team concludes that Homocysteine levels are dependent on Marsh classification and the regular use of B-vitamin supplements reduces of homocysteine levels in patients with celiac disease.The study confirms earlier studies suggesting that both the presence and severity of celiac disease determined homocysteine levels.
The regular use of supplemental B vitamins resulted in higher levels of serum vitamin B6, folate, vitamin B12 and lower levels of plasma homocysteine in patients with celiac disease. Moreover, supplemental B vitamins seem to offer protection against the effects of villous atrophy on homocysteine levels, independent of the genetic susceptibility status as determined by carriage of the C677T polymorphism of 5,10 methylenetetrahydrofolate reductase.
What do YOU think?
Bev
Replies to This Discussion
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Permalink Reply by Kristin H on -
Sorry long time no post, but I'm going to respond to this one. Sounds like those doctors are right on with the B-vitamins as being essential for us, but if we have a varied non-glutinous grain/seed grain/ bean-grain diet (incl. but not limited to: buckwheat, amarath, millet (? if you can handle it), sorghum, coconut flour, teff, brown rice, quinoa, nut-meals, mesquite, carob flour, garbanzo flour, soy, etc.), we do get a decent b-vitamin spectrum. However, I know that I am not exactly rolling in the money and tend to get on a grain "kick" then move on to another!
But I think a few other vitamins/minerals are very essential:
1) Magnesium: probably one of the most important for colon function/smooth muscle tone and healing. When your body is having trouble with absorbtion, keeping a good calcium/magnesium balance is challenging, and the balance of these two effects the receptors on all your cells!
2) Glutamine: an amino acid essential for muscle recovery, which, as you can see from the name, is found primarily in gluten. (Boo). Luckily, several companies make glutamine supplements from non-glutinous sources! If you are working out, this is a must.
3) (personal favorite, but to each his or her own): L-Arginine. I have found that time and time again when I am in some pain, taking an l-arginine supplement gives me energy and starts to remove some of the agony from my digestive tract. I have heard that l-arginine has a positive effect on blood sugar regulation and vascular dilation, so I think it may have something to do with increasing absorptive potential. I can't guarentee it will work for everyone, but in my case, l-arg has been a great helper. Bonus point: it's sold in the "sports nutrition" part of the store, so you get to venture into the land of giant protein tubs.
Sorry for length. Just want to share anything and everything I can. If it helps someone, I've done my part!
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